Rescue lists

Some double blind trials have rescue medication - usually a lower dose of the active treatment to be used for patients showing signs of intolerance. For such trials a rescue medication list can be managed by administrators in much the same way as the main code list. Here is an example of a rescue list:

Block Rescue code Site Treatment group On site? Used? Date used
1 R2001 UCL Placebo Yes No  
1 R2002 UCL Placebo Yes No  
1 R2003 UCL Low dose active Yes No  
1 R2004 UCL Placebo Yes No  
1 R2005 UCL Low dose active Yes No  
1 R2006 UCL Low dose active Yes No  

The rescue list provides a way for investigators when necessary to assign a rescue medication code that is linked to the patient’s randomisation code. The rescue code allows the investigator to remain blinded while lowering the dose of the treatment.

Viewing

For trials that have a rescue list a Rescue list link will be shown in the left-hand sidebar to administrators. The list can be searched in the same way as randomisation lists. Unlike randomisation lists however, all the detail available is shown in the list - clicking on an individual entry will not bring up further details.

Updating

Individual codes or blocks of unused codes can be assigned to different trial sites and marked as on site using the form provided. Only codes marked as on site and unused are available for rescue medication. Multiple codes or blocks can be updated by specifying lists (e.g. 3,7,8). In addition, multiple blocks can be specified with ranges (e.g. 1-6).

Notes may be added to codes in the list. This might be useful to record when kits are lost or damaged, or removed for testing etc.

Downloading

The full rescue list can be downloaded by clicking on the ‘Download as CSV’ link shown at the bottom of the listing. The rescue list will be sent as a plain text comma separated value file. The field names are given in the first row.

Page updated 1 May 2014 14:43