Randomisation and online databases for clinical trials

Sealed Envelope provide high quality online software applications for randomising patients into clinical trials and recording their case record form data.

Randomisation & Code break

Proven, reliable, centralised randomisation services to suit every type of clinical trial. Tell us about your clinical trial and we can set up a randomisation system to meet your requirements. With over 10 years of experience, and a range of automated systems for randomisation by internet, telephone or text message, you can trust Sealed Envelope with your trial.

Comprehensive randomisation service

Randomise patients online and optionally by telephone. Code breaking can also be performed by authorised users.

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Expert set-up
Customised to your trial
Control panel for trial managers

Simple randomisation service

We also offer a simple randomisation service intended for non-commercial clinical trials that do not require minimisation.

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Self service online set up
Free for up to 50 randomisations
Randomisation by text message

Red Pill

Red Pill is Sealed Envelope's online database application for electronic data capture (EDC) - recording case record form data for patients participating in clinical trials. Investigators enter forms directly online, and trial managers can manage the data in real time.

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Client testimonials

I have recommended Sealed Envelope to many of my colleagues because it is always reliable, efficient and helpful.

Belinda Lees Assistant Director, Royal Brompton Clinical Trials and Evaluation Unit

Fantastic good technical and academic support.

Professor Phillipa Hay

Personal service & help always at the end of an email. The system is very easy to use. You are willing to work with the customer to adapt the system to suit the requirements of the trial at the start and make any further changes as necessary during the course of the trial.

Sian Wells, former Trial Manager at Bristol CTEU

Very simple system, easy to use and backup support has been excellent. Team are always understanding and easy to talk too.

Diane Picton, Clinical Trial Monitor and co-ordinator

Reliable and easy to use.

Chris Rogers, Co-director Bristol CTEU

Easy and straightforward to use. I was able to set up my own randomisation account when I was designing a clinical trial for my dissertation.

Zoe Beardow, Critical Care Research Sister

Logging on is always quick and easy. The system is never down. The system is functional in its logic. The randomisation was very easy to set up and use.

Kate Levett, PhD student, UWS Australia

Good service, easy to use website - help available when needed.

Dr Barbara Sheil, Clinical Project Manager, Telethon Institute for Child Health Research, Perth, Western Australia

I think the functions and set-up processes to add new users/centres are easy to use and intuitive.

Margo Childs, TANDEM Trial Manager

I think it is an excellent, value-for-money service.

Sharon Hulme, Research Coordinator, Stroke & Vascular Centre, University of Manchester

Never seen a downtime, good customer service, technically good and requests for changes/updates are handled really well.

Mithun Sortur, Senior Clinical Data Manager, University of Oxford

The service is very easy to set up and use and is a very affordable solution.

Melissa Dobson, Operations Director

Clear, easy to use - no complicated instructions. Our statisticians like it.

Professor Janet Powell, Imperial College

User friendly databases, very intuitive and also flexible in terms of design.

Monica Yanez-Lopez, Data manager

Quick, easy and friendly

Lourdes Ibáñez, MD. Professor of Pediatrics, University of Barcelona

Easy and fast to use.

Doctor Gribel

Great product, great service. I've already recommended to over a dozen colleagues.

Gus Gazzard, Chief Investigator LiGHT Trial and Consultant Ophthalmic Surgeon

Helpful personal service, simple website

Caroline Coats, British Heart Foundation Research Fellow

Easy to use, the randomisation and eCRFs are simple and straightforward, training others to use these can be done remotely.

Steven Robertson, Senior Data Manager, Clinical Trials Unit at LSHTM.

The system we have set up is easy to use and it does exactly what it says on the tin.

Stella Silvester, Trial Co-ordinator, University of Cambridge

System is fully bespoke which is very useful for our department as each trial is different! Excellent and efficient communication with developers.

Daphne Babalis, Trial Manager CTEU

Ease of set up and very easy to use/access.

Emma Hedley, Senior Clinical Trials Manager

I would absolutely recommend Sealed Envelope to colleagues: The ability to link in the randomisation facility for our clinical trial to the database; The ease of use of the CRF builder, relatively easy to understand and easy to get up to speed with all functions available; Support is readily available when required.

Mr Neil Nathwani, Research Optometrist

Sealed Envelope have provided us with an efficient service in setting up an online screening, randomisation and data collection service for our clinical trial (ECST-2). This has involved several iterations of the development process and they have been patient and helpful at each stage.

Roland L Featherstone, Trial Manager, The 2nd European Carotid Surgery Trial (ECST-2)

Efficient and straightforward service, runs perfectly.

Ona McCarthy, Research and Trial Coordinator

I love it.

Dan Horner, Research fellow, Emergency Medicicne / Critical care, University of Manchester / Central Manchester University Hospitals NHS Foundation Trust